Andy Reid, Kansas City Chiefs
Sep 8, 2013; Jacksonville, FL, USA; Kansas City Chiefs head coach Andy Reid during the game against the Jacksonville Jaguars at EverBank Field. Mandatory Credit: Rob Foldy-USA TODAY Sports

NFL Week 5 2022: 5 best games of the weekend

Looking at the NFL Week 5 slate, these are the five games we all need to sit down and watch this autumn weekend.

5. Los Angeles Chargers (-2) at Cleveland Browns

Both teams are 2-2 and have a chance to earn a huge win here. The loser will be feeling blue, knowing it’ll take at least a few weeks to eclipse the .50 mark. And, for the Browns, that proposition is terrifying considering how hard their schedule is over the next six weeks. If Cleveland is going to pull the upset win at home, it’ll be on the legs of Kareem Hunt and Nick Chubb, facing one of the league’s worst run defenses. For the Chargers, it’s about making Jacoby Brissett need to beat you in long down and distances.


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4. Philadelphia Eagles (-5.5) at Arizona Cardinals

Can the Cardinals give the Eagles their first loss of the season? Philadelphia is the only unbeaten team remaining in the league, and it’s largely because Jalen Hurts is playing like the NFL MVP through four weeks. This might be the biggest test yet for Hurts and Co., going across the country to play the talented, yet flawed, Cards. Arizona is 2-2 and desperately needs more from quarterback Kyler Murray. Can he deliver and start making believers of the Cardinals once again?

3. Dallas Cowboys at Los Angeles Rams (-5.5)

The Rams are 2-2 while the Cowboys are riding a three-game win streak while quarterback Dak Prescott recovers from a broken thumb. If Dallas wins this game, there will be talk about whether the Cowboys are contenders. If Los Angeles wins, it’ll be the win the Rams have been looking for all year after a rough four weeks to start the season. This likely comes down to who can block better.

2. Las Vegas Raiders at Kansas City Chiefs (-7)

This Monday night showdown between two AFL rivals should be fun. Kansas City and Las Vegas are both coming off victories, but this is a big moment for both. The Raiders are 1-3 and a loss here all but ruins any hopes of catching the Chiefs in the AFC West. For Patrick Mahomes and his squad, a win brings them to 4-1 before hosting the Buffalo Bills.

1. Cincinnati Bengals at Baltimore Ravens (-3.5)

This should be a terrific AFC North clash on Sunday night. The Ravens and Bengals are both 2-2 and playing for either a share of or the outright lead in the division (depending on Cleveland). Can Baltimore curtail Joe Burrow? Can Cincinnati limit Lamar Jackson? Expect fireworks.

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