NFL Week 10 odds: 5 best bets on underdogs

NFL Week 10 kicks off with the Raiders VS the Chargers on Thursday Night Football. We take a look at five underdogs bets in NFL Week 10.

5. Arizona Cardinals (+4.5) at Tampa Bay Buccaneers

The Buccaneers should win the game, but the Cardinals have been putting up a fight each week. Last Thursday, the San Francisco 49ers were given a scare in the desert, only winning by three points. Now, Arizona has 10 days off to prepare for Tampa Bay, which is coming off a tough 40-34 overtime defeat to the Seattle Seahawks. The Cardinals actually have the better record, and while they need to come cross-country, they’re equipped to hang tough throughout.

4. Pittsburgh Steelers (+3.5) vs. Los Angeles Rams

The Rams are going to be without wide receiver Brandin Cooks, who remains in concussion protocol. Considering Jared Goff has been middling this year, that doesn’t bode well for the Rams. Pittsburgh has struggled offensively without Ben Roethlisberger, but the defense has been one of the league’s better units. Look for the Steelers to get pressure up front behind T.J. Watt and shut off Todd Gurley’s running lanes. Los Angeles is the better team, but there isn’t much reason to believe it’ll blow Pittsburgh out.

Want $250 to bet on NFL Week 10?

3. Seattle Seahawks (+6) at San Francisco 49ers

The 49ers are the league’s last undefeated team. The Seahawks are also 7-2 and damn good in their own respect. Seattle shouldn’t be getting six points against anybody, home or away. And while the Seahawks are typically much better in their own building, this year has seen Seattle play better on the road. In fact, the Seahawks are yet to lose a game away from CenturyLink Field this season. This game is much closer to being a proverbial coin flip than it is a six-point spread.

Read: Lamar Jackson is Firmly Focused on the Postseason

2. Miami Dolphins (+10) at Indianapolis Colts

Every game the Colts have played this year has been a one-score affair. While the Dolphins are certainly one of the league’s worst teams, they’ve played better in the past month including a win over the New York Jets on Sunday. In contrast, the Colts are struggling after losing to the Steelers, primarily due to health. Indianapolis could be without starting quarterback Jacoby Brissett along with receivers T.Y. Hilton, Parris Campbell and Devin Funchess on offense. Miami won’t win, but it should cover the double-digit spread.

1. Buffalo Bills (+3) at Cleveland Browns

This is an easy call. The Bills have beaten up on a bunch of bad teams, but guess what? Cleveland is a bad team. The Browns are 2-6 and Baker Mayfield has thrown seven touchdowns against 12 interceptions. Brutal. The Bills might not be good enough to beat the NFL’s elite, but getting three points against a two-win Browns team? Insane.