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NFL Week 4 odds: 5 best bets on favorites

After taking a deep dive into the NFL Week 4 odds, these five favorites make the most sense to both win and over their respective spreads.

5. Green Bay Packers (-7) vs. Pittsburgh Steelers

The Steelers go limping into Lambeau Field this weekend after being handled with relative ease by the Las Vegas Raiders and Cincinnati Bengals over the past two games, both at Heinz Field. Now, the Packers welcome Ben Roethlisberger and Co. into Titletown, and while Green Bay has some defensive issues and injuries to deal with, can the Steelers take advantage? This seems like a spot where the Packers’ offense makes enough plays against Pittsburgh’s vaunted front, and then capitalizes on a few turnovers to blow the game open.


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4. Los Angeles Rams (-4.5) vs. Arizona Cardinals

This line initially opened at six points in most books but quickly shrunk. Why? The Rams have been the best team in football thus far, pounding the Chicago Bears and Tampa Bay Buccaneers at home while winning a three-0point affair over the Indianapolis Colts on the road. Meanwhile, the Cardinals struggled to beat the Jacksonville Jaguars on Sunday and should have lost to the Minnesota Vikings in Week 2. This Los Angeles defense is no joke, and it’ll be a problem for Arizona.

3. Tennessee Titans (-6) at New York Jets

Have you seen the Jets? Yes, the Titans are going to be without both star receivers in A.J. Brown and Julio Jones, but does it matter? New York is yet to score 14 points in a game and hasn’t scored a touchdown in two weeks. The Titans basically need to put 20 points on the board and you can start counting your money. Zach Wilson, Jets rookie quarterback and No. 2 overall pick, also leads the league with seven interceptions. Yikes.


Read: NFL Week 4 Odds – 5 Best Bets On Underdogs


2. Dallas Cowboys (-4.5) vs. Carolina Panthers

Yes, this is a rest mismatch. Dallas is coming off a short week after beating the Philadelphia Eagles on Monday night, while Carolina has 10 days rest not having played since last Thursday. However, the Cowboys’ offense is rolling and the Panthers are now without All-Pro running back Christian McCaffrey and star rookie corner Jaycee Horn. It could be rough going for the Panthers as they adjust to life without their best player.

1. Tampa Bay Buccaneers (-7) at New England Patriots

Tom Brady is going to want to take apart the Patriots at the joints on national television come Sunday night, especially in his old haunt. Unfortunately for the Patriots, the Bucs have far more talent on both sides of the ball. Like always, expect Brady to get his.

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