Matthew Stafford, Sean McVay, Rams
May 27, 2021; Thousand Oaks, CA, USA; Los Angeles Rams head coach Sean McVay speaks with quarterback Matthew Stafford (9) during oraganized team activities. Mandatory Credit: Gary A. Vasquez-USA TODAY Sports
Home » Blog » NFL Week 5 2022: A case for each favorite

NFL Week 5 2022: A case for each favorite

The NFL Week 5 lines are out, and we look at how each favorite can cover their respective spreads this weekend.

Indianapolis Colts at Denver Broncos (-3.5)

The Broncos have been underwhelming, but the Colts are a mess. Denver gets Indy on the road, banged up, on a short week.

New York Giants at Green Bay Packers (-8)

This game will be played in London, but it could be played on the moon. The Packers are better than the Giants in every phase of the game.

Pittsburgh Steelers at Buffalo Bills (-14)

Have you seen the Steelers’ offense? It’s like watching people learn the sport in real time. The line could be 28 points.

Los Angeles Chargers (-3) at Cleveland Browns

After beating the Texans, the Chargers are potentially getting receiver Keenan Allen back and now face another limited offense. Good news for Justin Herbert.

Chicago Bears at Minnesota Vikings (-7)

The Bears can’t score, and while the Vikings typically invite lesser teams to hang around, the Bears might not accept the invitation.


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Detroit Lions at New England Patriots (-3)

The Lions can’t stop anybody. If Mac Jones plays, he should throw the ball all over Detroit’s overwhelmed defense.

Seattle Seahawks at New Orleans Saints (-6)

This is a must-win for the Saints, but let’s be real … tough spot. Long travel from England, and now getting a Seahawks team that can score. However, New Orleans has playmakers as well.

Miami Dolphins (-3) at New York Jets

Even with Teddy Bridgewater, the Dolphins are a much better team than the Jets, who are 2-2 but incredibly lucky to not be 0-4.

Atlanta Falcons at Tampa Bay Buccaneers (-8)

The Falcons have been fun, but Tom Brady isn’t losing three straight. Look for the Bucs to get right in a big way.

Tennessee Titans (-2.5) at Washington Commanders

Tennessee is playing well, winning two straight. Meanwhile, Washington has lost three consecutive games and Carson Wentz looks lost.

Houston Texans at Jacksonville Jaguars (-7)

The Jaguars are simply a better team, coming home after a two-game road trip. Jacksonville should move the ball at will.

San Francisco 49ers (-5) at Carolina Panthers

Baker Mayfield and Matt Rhule are involved.

Dallas Cowboys at Los Angeles Rams (-4.5)

The Rams are struggling offensively, but the defensive front could make this a long day for Cooper Rush.

Philadelphia Eagles (-5) at Arizona Cardinals

The Cardinals are a mess on both sides of the ball. Look for the trenches to be dominated by the Eagles.

Cincinnati Bengals at Baltimore Ravens (-3)

Lamar Jackson is a one-man band, but what a band. Cincinnati could have a hard time containing him. On defense, Baltimore just needs a few big plays.

Las Vegas Raiders at Kansas City Chiefs (-7)

Patrick Mahomes destroys AFC West opponents. Bad news for the Raiders, who happen to play in said division.

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