The Southern Illinois Salukis men's basketball team represents Southern Illinois University Carbondale in Carbondale, Illinois. The Salukis compete in the Missouri Valley Conference, and they play their home games at Banterra Center. As of March 2019, Saluki Hall of Fame basketball player, Bryan Mullins, has become the newest head coach of the Southern Illinois basketball program.
Prior to joining the NCAA, the Salukis competed in the NAIA men's basketball. Appearing five times, with a combined tournament record of 9 wins and 4 losses. Most notable tournament appearances came in 1945, in which the Salukis finished third, and then the following year in the 1946 tournament where the Salukis were NAIA national champions. The Salukis would not place again in the following three tournament appearances in 1947, 1948, 1960.